Draw the structure of the neutral product formed in the following reaction of dimethyl malonate and methyl vinyl ketone.

Question

Question:

Draw the structure of the neutral product formed in the following reaction of dimethyl malonate and methyl vinyl ketone.

 

Answer:

1,4-assault(attack):
Conjugated assault(attack) by a nucleophile is called as 1,4-assault or Micheal assault. This sort of assault is finished by a delicate nucleophilic site. For instance, Gilman reagent assaults the vinyl ketones along these lines.

Explanation:
The alpha hydrogen particles of the dimethyl malonate are extremely acidic in light of the fact that after deprotonation of that hydrogen the conjugate base is balanced out by two contiguous carbonyl gatherings.
In this response, methanolate goes about as a base and deprotonate the acidic alpha hydrogen molecule of the dimethyl malonate and structure an enolate. The enolate go about as a nucleophile and 1,4-assault happens to the methyl vinyl ketone. After protonation, the last item is shaped.

 

The structure of the final product is shown above.

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